As it pertains to "Enterprise" and Python, I think the most interesting project is OpenStack. I don't use OpenStack but it has been interesting that in conversations with Enterprise devs/managers OpenStack has come up several times. It turns out Enterprise is still really skeptical of the public cloud and are going through the efforts of running their own IaaS/PaaS internally. In my experience OpenStack seems to be coming up much more frequently than CloudFoundry.

And for the record, by Enterprise I'm not talking Silicon Valley Enterprises. These are strictly non-tech Enterprises that traditionally view anything software related as a cost center.